
Doctor-led ZO 3-Step Peel in Marylebone, London for pigmentation, melasma, acne and texture. Medical-grade resurfacing from £350. Book with Dr Joney De Souza.
Professional medical-grade retinol peel for improved skin texture, tone and clarity at Dr Joney De Souza Clinic, London
If your complexion looks dull, marked or uneven no matter how carefully you look after it, a medical peel can reset your skin from the surface down. Dr Joney De Souza Clinic offers the ZO 3-Step Peel to patients who want a structured, doctor-supervised way to improve skin health rather than a quick facial fix.
This treatment suits you if you recognise any of the following:
This peel is at its best refining tone, texture and clarity and softening surface pigmentation and fine lines. If your priority is restoring volume, lifting sagging or smoothing deep set wrinkles, we can guide you to the right option. Your practitioner confirms suitability at your consultation, choosing a gentler route if your skin is currently inflamed, broken or actively sun-damaged, and a retinol-based peel is not recommended during pregnancy or breastfeeding.

The ZO 3-Step Peel is a professional retinol-based chemical peel developed by ZO Skin Health. At Dr Joney De Souza Clinic in Marylebone, your practitioner applies it in clinic, delivering medical-grade retinol, salicylic acid and lactic acid to resurface and renew the skin. The treatment addresses several concerns at once, lifting texture, tone and clarity in a single procedure.
The peel speeds up cellular turnover, softens the look of pigmentation and fine lines, and primes the skin for the ZO Skin Health home programme. Over the days that follow, your skin goes through a controlled exfoliation, and visibly fresher skin emerges as it renews.
Related treatments at Dr Joney De Souza: Enerpeel chemical peels, HydraFacial, SkinPen microneedling and dull skin.
Many patients notice visibly improved skin clarity, texture and tone following the ZO 3-Step Peel. In most cases, the skin appears clearer and more refined within five to seven days as the exfoliation phase completes and fresh skin emerges.
Furthermore, with a structured home programme patients can sustain and build on these improvements over time. Individual results vary, and Dr De Souza will advise on realistic outcomes at your consultation.


ZO® Non-Hydroquinone Hyperpigmentation System


ZO® Multi-Therapy Hydroquinone System


ZO-Multi-Therapy Hydroquinone System
Your practitioner applies the ZO 3-Step Peel using a precise, controlled technique developed for in-clinic use. The peel combines retinol with salicylic acid and lactic acid to exfoliate the skin surface, prompt cellular renewal and address pigmentation, congestion and fine lines in a single session. Several corrective actions happen at once, so you are not treating one concern in isolation while another goes untouched.
The treatment is tailored to your skin type and concerns. Your practitioner assesses your skin at consultation to choose the right application technique and to confirm the peel suits your skin condition on the day of your appointment.
Before treatment begins, your practitioner assesses your skin in detail, reviewing your skin type, concerns and current condition to confirm the ZO 3-Step Peel is right for you and to plan the correct application. This personalised assessment means the treatment is calibrated to your skin rather than run to a fixed protocol.
Your practitioner then cleanses the skin thoroughly to lift makeup, oils and impurities. This step lets the peel solution penetrate evenly and keeps the active ingredients in optimal condition. A careful preparation makes a real difference to how well the peel that follows performs.
Your practitioner applies the ZO 3-Step Peel solution in a controlled way, working methodically across the treatment area. The blend of retinol, salicylic acid and lactic acid starts exfoliating and renewing the skin at once. This step sets the depth and evenness of the peel, so clinical precision here shapes your final result.
Straight after the peel, your practitioner reviews the skin and takes you through your aftercare in full, with specific guidance on products, sun protection and activities to avoid before you leave. You will also learn what to expect during the exfoliation phase over the following days.
In the days after treatment, the skin goes through a controlled exfoliation as the retinol and acid complex keeps working. Some patients notice flaking, mild dryness or tightness during this phase. This is entirely expected and signals that cellular renewal is under way. Fresher skin usually emerges within five to seven days of the peel.
After the peel, your practitioner may recommend a ZO Skin Health home programme to maintain and build on the in-clinic result. Patients who pair the peel with a consistent medical-grade home routine tend to see the most sustained improvement in texture, tone and clarity over time. Your practitioner can plan repeat peels at sensible intervals, guided by how your skin responds.
Every ZO 3-Step Peel at Dr Joney De Souza Clinic begins with a personalised consultation. Your practitioner takes time to understand your skin concerns, assess your skin condition and confirm the peel is right for how your skin presents on the day, so the plan is built around your skin rather than a fixed protocol.
Arrive with clean skin and no makeup. Your practitioner will advise whether to pause retinoids or active acids in the days before your appointment. At consultation, they assess your skin in full, talk through your concerns and confirm the treatment suits you. This is also your chance to ask anything about what happens during and after the peel. No numbing is needed, as the procedure is comfortable without it.
Your practitioner applies the peel solution precisely and methodically across the treatment area. Most patients feel a mild tingling during application, which settles quickly. The active part of the appointment is usually done within 30 minutes. You can return to your usual day straight afterwards, though mild redness or sensitivity may show for a short while.
Over the following days, the skin moves through a controlled exfoliation phase. Some flaking, dryness or tightness is normal as the skin renews, so avoid picking or peeling it. Use gentle skincare only, apply SPF daily and skip active acids or retinoids until the exfoliation phase has fully resolved. Avoid excess heat, sun exposure and strenuous exercise for 48 hours after treatment. Fresh skin is typically visible within five to seven days.
The ZO 3-Step Peel is offered at many clinics across London, yet where a retinol peel is applied without proper skin assessment there is real risk of an uneven or unpredictable result. At Dr Joney De Souza Clinic, every treatment is delivered in a doctor-led setting, where clinical assessment, technique and patient safety sit at the centre of each appointment. Dr Joney De Souza brings more than two decades of aesthetic medicine experience and a precise, considered approach to skin treatment.
Carried out by Dr Joney De Souza or a member of our clinical team. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci.
My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results.
Dr Joney De Souza, The Sybarite
A chemical peel applied without careful assessment carries risk, which is why the approach here reflects the clinic’s commitment to clinical care: thorough assessment, precise application and clear aftercare guidance so your result is exactly as intended.
Dr Joney De Souza Clinic prices the ZO 3-Step Peel according to the treatment area and the full clinical appointment. Your fee reflects the doctor-led consultation, the personalised application technique and the aftercare included with every treatment. The ZO 3-Step Peel starts from £350.
The peel is most often performed on the face, with the option to extend to the neck and decolletage if these areas concern you. After consultation, your practitioner confirms the most suitable treatment area and advises whether a single session or a series of peels fits your skin goals. Patients with more significant pigmentation or texture concerns usually benefit from planning a structured course from the outset.
| Treatment | Price (£) |
|---|---|
Face | £350 |
Face & Neck | £450 |
Face, Neck & Décolletage | £550 |
The ZO 3-Step Peel and HydraFacial are both popular skin treatments at Dr Joney De Souza Clinic, but they work differently and suit different concerns. The ZO 3-Step Peel is a retinol-based chemical peel that speeds cellular renewal through controlled exfoliation. It suits patients troubled by pigmentation, uneven texture, acne marks or dullness, and it pairs an in-clinic procedure with a medical-grade home programme for lasting results.
HydraFacial, by contrast, is a multi-step hydradermabrasion treatment that cleanses, exfoliates, extracts and infuses the skin with hydrating serums in one session. It suits patients who want immediate brightness and hydration with no exfoliation phase and little preparation. The choice between the two is guided by your individual skin assessment, and some patients gain from including both as part of a longer-term skin health plan.

The ZO 3-Step Peel is one of the most asked-about skin treatments at Dr Joney De Souza Clinic. The questions below cover what patients most often raise at consultation, from how the peel works and what to expect to who it suits and how it compares with other skin treatments available in Marylebone, London.
The ZO 3-Step Peel is a professional, medical-grade chemical peel developed by Dr Zein Obagi that combines an in-clinic treatment with a take-home kit. At Dr Joney De Souza Clinic in Marylebone, your practitioner uses it to exfoliate, stimulate collagen and improve tone and texture over the days that follow. The in-clinic step leads into a guided at-home stage that extends and enhances the result, so you get a deeper, more sustained improvement than a one-off surface peel.
It works particularly well for pigmentation and melasma, sun damage, acne and breakouts, fine lines and dull, uneven texture. The pairing of in-clinic and at-home steps makes it well suited to more stubborn tone and texture concerns. Your practitioner tailors the protocol to your skin and goals and confirms suitability at your consultation. It is not designed to restore lost volume or lift sagging skin, so for those concerns a different treatment may be recommended.
The in-clinic step applies the peel and prompts renewal, and the take-home stage continues the process over the following days for the full benefit. The at-home stage is an essential part of the treatment, and your practitioner explains exactly how to use it. Following the kit as directed is what delivers the deeper, longer-lasting result, and you are guided through every step before you leave.
Expect some visible peeling and flaking over roughly three to five days as the skin renews, along with mild redness and tightness. This is a normal, expected part of how the treatment works, and many patients plan it around their schedule for this reason. We recommend daily SPF and avoiding sun throughout.
Once the peeling settles, usually within a week, the skin looks brighter, smoother and more even. Results keep improving as collagen renews over the following weeks. With good skincare and sun protection the improvement lasts well, and the peel can be repeated periodically. Your practitioner will advise on timing for any repeat treatment.
Yes. It complements a medical skincare routine and works well alongside other resurfacing options such as Enerpeel peels or a HydraFacial for ongoing maintenance. For deeper concerns, your practitioner may suggest combining it with other treatments over time and will advise the right sequence at your consultation. This planned approach keeps results consistent.
The ZO protocol suits many skin types, though darker skin needs careful assessment and the correct preparation to minimise any risk of pigmentation change. A doctor-led consultation matters here for that reason. Your practitioner reviews your skin type and history and prepares the skin appropriately, and this medical oversight keeps the peel both safe and effective.
The ZO 3-Step Peel starts from £350, which includes the in-clinic treatment, the take-home kit and the doctor-led consultation. You can see the full breakdown on our pricing page. To book, reach us by WhatsApp, phone or online. Dr Joney De Souza Clinic sits in Marylebone, central London, close to Bond Street, Baker Street and Marble Arch.
Carried out by Dr Joney De Souza or a member of our clinical team. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Your practitioner assesses your skin, plans the application and takes you through aftercare, so the treatment is delivered and overseen within a doctor-led setting from start to finish.
Follow the take-home steps exactly as directed, keep the skin moisturised, and let the peeling happen naturally without picking. Apply SPF 50 every morning and avoid direct sun, saunas and strong active ingredients while the skin renews. Most importantly, complete the full at-home stage for the best result. Your practitioner provides detailed written instructions before you leave.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.