
Skin rejuvenation with Picosure Laser is the latest and most advanced skin revitalisation treatment with very little downtime. It can dramatically reduce pigmentation, and melasma whilst boosting collagen and reducing lines and wrinkles.
Many patients seeking tighter, more youthful skin also want to correct uneven pigmentation, including melasma, post-inflammatory hyperpigmentation, and age/sun-related pigmentation. Pigmentation develops when melanin (the pigment that gives skin its colour) becomes overproduced in certain areas due to factors such as sun damage through UV exposure, hormonal changes, or inflammation after acne or injury.
Left untreated, these patches can make skin look dull, uneven and aged beyond your years. While topical creams can help mild cases, deeper or stubborn pigmentation often requires advanced technology to break down pigment effectively without excessive downtime.
PicoSure is one of the most sophisticated facial rejuvenation pico lasers available today. At Dr Joney De Souza Clinic in Marylebone, London we use PicoSure to treat pigmentation, hyperpigmentation, dark spots, acne scarring, dullness, fine lines and even unwanted facial tattoos with exceptional precision and minimal downtime.
PicoSure’s ultra-fast picosecond pulses allow us to rejuvenate the skin gently yet effectively while preserving the skin’s natural integrity and luminosity. Uneven pigmentation is one of the most common concerns for facial rejuvenation. Sun exposure, hormonal fluctuations and past inflammation can all leave the skin marked or uneven.
PicoSure targets facial pigment with remarkable precision. The picosecond pulses break pigment into tiny particles that the body naturally clears over time. This technique allows us to improve:
Age spots and sun-induced pigmentation
Melasma (with appropriate protocols)
Freckles and diffuse discolouration
Post-inflammatory pigmentation from breakouts
Treatment brightens the complexion, leaving the skin clearer, more even and naturally radiant. Most patients notice improvements within weeks, with continued refinement over a course of sessions


Dark spots (also known as solar lentigines or ‘sun spots’) and age spots develop over time from chronic sun exposure, UV damage and the natural ageing process. These spots are typically flatter and darker than your normal skin tone, and while harmless, they can be cosmetically bothersome and make skin appear prematurely aged.
Treatment options and results vary depending on depth and colour of the spots, but laser technology remains one of the most reliable solutions for faster, noticeable results as seen in the press.
PicoSure targets pigment precisely and breaks it down without significant heat build-up
PicoSure encourages new collagen production, improving overall skin texture and tone
PicoSure is safe on most skin types when used expertly
Multiple spots can be treated in a single PicoSure pico laser session
Unlike chemical peels or brightening creams which act more slowly and superficially, PicoSure addresses pigment deep within the skin, meaning many patients see improvement after just one to a few sessions.








Many of our patients at Dr Joney De Souza in Marylebone are considering a “glass skin treatment”. Glass skin describes skin that appears exceptionally smooth, clear and luminous, with refined pores and an even tone. Rather than looking tight or treated, the skin looks hydrated, polished and naturally radiant, almost reflective under light. It is a finish that comes from excellent skin quality rather than added volume or heavy resurfacing.
PicoSure is one of the most effective pico laser treatments for creating a Glass skin effect. By stimulating collagen and elastin while improving pigmentation and texture, PicoSure enhances overall skin clarity and radiance. The result is smoother, brighter skin with a refined surface rather than obvious tightening or peeling.
PicoSure works through a photo acoustic effect that triggers collagen renewal without damaging the skin surface. This helps refine pores, improve skin smoothness and even out tone. When skin structure becomes healthier and more uniform, light reflects more evenly, creating the luminous glass skin appearance.
What our Clients say
‘I had the Picosure laser treatment because I’m a novice to laser treatments and I wanted something which would help to rejuvenate my skin, make it glow but give me as little downtime as possible’
The Picosure Laser is the perfect way to correct hyperpigmentation and to improve overall skin tone, quality and texture. Best results can be achieved following a course of Picosure laser treatment. Using gentle Picosure laser stimulation, just four treatments a year can help to reduce the appearance of fine lines, wrinkles, pores and pigmentation.
Pico laser, also known as picosecond laser, is an advanced laser treatment that uses ultra short bursts of energy measured in trillionths of a second to target pigment, ink, and damaged skin cells. These rapid pulses shatter pigment into microscopic particles that are then naturally cleared by the body. Because the energy is delivered so quickly, pico laser treatment causes minimal heat damage, making it safer, more precise, and suitable for a wide range of skin types. Contact us for your pico laser treatment in London.
What is Pico Laser tattoo removal?
Pico laser tattoo removal uses the same ultra short pulse technology to break tattoo ink into very small particles. This allows for more effective ink clearance, often with fewer sessions and less damage to surrounding skin compared to older laser technologies.
Yes. PicoSure Treatment in our Marylebone clinic is highly effective for treating unwanted pigmentation by delivering ultra short pulses of energy that break pigment into tiny particles. These are then naturally cleared by the body over time. It is commonly used for conditions such as sun spots, age spots and uneven skin tone, helping to create a clearer and more even complexion without significant downtime.
PicoSure laser treatment is an excellent option for sun damaged skin. Years of UV exposure can lead to brown spots, patchy pigmentation and dullness. PicoSure targets this excess pigment while also stimulating collagen, which can improve overall skin quality and brightness alongside pigment reduction.
Yes. PicoSure is particularly well suited to treating dark spots caused by sun exposure, ageing or post inflammatory pigmentation. By shattering the pigment rather than heating surrounding tissue, it allows for precise treatment of dark spots with a lower risk of damage to healthy skin.
Expert physician-led treatment with precise energy selection for each area of the face.
Minimal downtime compared with traditional resurfacing lasers.
Suitable for a wide range of skin types thanks to its low heat profile.
Tailored treatment plans that integrate seamlessly with injectables, skincare and advanced aesthetic protocols.
Natural, elegant outcomes that focus on clarity, refinement and healthy radiance.
Pico laser like Picosure Focus is highly effective for targeting pigmentation such as sun spots, age spots, melasma, freckles, and uneven skin tone. It can also help improve overall skin clarity, brightness and texture.
The pico laser lens delivers picosecond pulses of energy that shatter pigment into tiny particles without damaging surrounding tissue. This process stimulates natural skin renewal and collagen production for clearer, smoother-looking skin.
Most patients benefit from 2–4 sessions, spaced 2–4 weeks apart, depending on the amount and depth of pigmentation being treated. Some types of pigmentation, such as melasma, may require more gradual treatment plans.
Downtime is minimal for Picosure laser treatments. You may experience mild redness for a few hours, and some pigmentation may temporarily darken before naturally flaking or fading over several days. Makeup can usually be worn the next day.
Most patients describe the sensation as a series of quick snaps or warmth on the skin. The treatment is generally well tolerated, and the device’s advanced technology helps maintain comfort throughout.
No. PicoSure works through a photo acoustic effect rather than traditional heat based lasers. This means it breaks down pigment with minimal thermal damage, resulting in a gentler treatment, faster recovery and a lower risk of complications when compared with older laser technologies.
PicoSure can be used on a wide range of skin tones when performed by an experienced medical practitioner. Its picosecond technology reduces excess heat, which lowers the risk of post treatment pigmentation issues. A thorough consultation is essential to assess suitability and tailor settings safely.
Most patients notice brightening and more even tone within 2–3 weeks, with deeper clarity achieved through a course of treatments.
PicoSure can be suitable for a range of skin tones when used with appropriate settings and clinical judgement. Careful assessment is essential to minimise the risk of pigmentation changes, which is why treatment should always be performed by an experienced medical practitioner.
Every PicoSure Focus treatment at Dr Joney De Souza Clinic begins with a thorough consultation. During this appointment, our expert team will assess your skin, discuss your concerns and review your medical history to determine the most effective approach. If you are looking for more information about what is involved with a PicoSure consultation or treatment, speak to our team.
| Your PicoSure treatment at Dr Joney De Souza |
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The team will explain how the PicoSure lens works, what improvements you can expect and how many sessions may be recommended for optimal results. |
Once your personalised plan is agreed, the skin is carefully cleansed and protective eyewear is applied. The PicoSure laser is then used to deliver ultra-short picosecond pulses of energy across the treatment area. These pulses target pigmentation, sun damage and uneven tone while stimulating natural collagen regeneration. Most sessions take around 15–30 minutes, and patients usually describe the sensation as a quick, warm “snap” on the skin with minimal discomfort. |
After treatment, the skin may appear slightly pink or feel warm for a few hours. Some pigmentation may temporarily darken before gradually fading as the skin renews. The tean will provide a tailored aftercare plan, which may include gentle skincare, moisturiser and strict sun protection to support the healing process. |
There is very little downtime with PicoSure Focus. Most patients return to normal activities immediately, and makeup can often be applied the next day. Over the following weeks, the skin becomes clearer, brighter and more even in tone as collagen production increases. A review appointment may be recommended to assess your progress and plan any follow-up treatments. |
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.