Hand Rejuvenation in Marylebone

Doctor-led hand rejuvenation in Marylebone for age spots, volume loss and skin quality: dermal fillers, Radiesse, Profhilo, PicoSure and peels.

At Dr Joney De Souza in Marylebone, we rejuvenate ageing hands to restoring lost volume, refreshing skin quality and fading pigmentation, with a plan tailored to your main concern.

Hand Rejuvenation Treatments Compared

At Dr Joney De Souza in Marylebone, the right approach depends on your main concern – lost volume, skin quality, or pigmentation. Here is how the core options compare.

Dermal Fillers & RadiesseRestore volume, soften veins & tendonsProfhilo & Skin BoostersHydrate and firm thin, crepey skinPicoSure & IPLFade age spots and sun damageEnerpeel & HydraFacialBrighten and smooth surface texture
Best forDermal Fillers & Radiesse
Bony, hollow hands with prominent veins/tendons
Profhilo & Skin Boosters
Dull, dehydrated or crepey skin
PicoSure & IPL
Brown spots, uneven tone, sun damage
Enerpeel & HydraFacial
Rough texture, dullness &maintenance
How it worksDermal Fillers & Radiesse
HA filler or Radiesse (CaHa) adds volume; Radiesse also stimulates new collagen
Profhilo & Skin Boosters
Injectable HA remodels and hydrates the skin over a course
PicoSure & IPL
Laser/light energy targets pigment, which the body clears
Enerpeel & HydraFacial
A gentle peel or medical facial resurfaces the top layer
DowntimeDermal Fillers & Radiesse
Minimal – mild swelling or bruising
Profhilo & Skin Boosters
Minimal
PicoSure & IPL
Minimal to short
Enerpeel & HydraFacial
Short
SensationDermal Fillers & Radiesse
Brief injection discomfort; numbing available
Profhilo & Skin Boosters
Small injection points
PicoSure & IPL
Warm, elastic-band pulses
Enerpeel & HydraFacial
Mild tingling
SessionsDermal Fillers & Radiesse
Often one (top-up as needed)
Profhilo & Skin Boosters
A course of two, ~4 weeks apart
PicoSure & IPL
A course, spaced a few weeks apart
Enerpeel & HydraFacial
Single or short course
LongevityDermal Fillers & Radiesse
~9–18 months (HA); Radiesse builds gradually for longer
Profhilo & Skin Boosters
Several months; maintained with repeat courses
PicoSure & IPL
Long-term with sun protection & skincare
Enerpeel & HydraFacial
Variable; best maintained regularly
Can be combined?Dermal Fillers & Radiesse
Yes – pairs well with pigmentation & skin-quality work
Profhilo & Skin Boosters
Yes – complements filler and laser
PicoSure & IPL
Yes – often staged with volume/skin-quality work
Enerpeel & HydraFacial
Yes – ideal as ongoing maintenance
See detailsSee detailsSee detailsSee details
Dermal Fillers & RadiesseRestore volume, soften veins & tendons
Best for
Bony, hollow hands with prominent veins/tendons
How it works
HA filler or Radiesse (CaHa) adds volume; Radiesse also stimulates new collagen
Downtime
Minimal – mild swelling or bruising
Sensation
Brief injection discomfort; numbing available
Sessions
Often one (top-up as needed)
Longevity
~9–18 months (HA); Radiesse builds gradually for longer
Can be combined?
Yes – pairs well with pigmentation & skin-quality work
See details
Profhilo & Skin BoostersHydrate and firm thin, crepey skin
Best for
Dull, dehydrated or crepey skin
How it works
Injectable HA remodels and hydrates the skin over a course
Downtime
Minimal
Sensation
Small injection points
Sessions
A course of two, ~4 weeks apart
Longevity
Several months; maintained with repeat courses
Can be combined?
Yes – complements filler and laser
See details
PicoSure & IPLFade age spots and sun damage
Best for
Brown spots, uneven tone, sun damage
How it works
Laser/light energy targets pigment, which the body clears
Downtime
Minimal to short
Sensation
Warm, elastic-band pulses
Sessions
A course, spaced a few weeks apart
Longevity
Long-term with sun protection & skincare
Can be combined?
Yes – often staged with volume/skin-quality work
See details
Enerpeel & HydraFacialBrighten and smooth surface texture
Best for
Rough texture, dullness &maintenance
How it works
A gentle peel or medical facial resurfaces the top layer
Downtime
Short
Sensation
Mild tingling
Sessions
Single or short course
Longevity
Variable; best maintained regularly
Can be combined?
Yes – ideal as ongoing maintenance
See details

Dermal Fillers & Radiesse for Hands

When the back of the hand loses its natural padding, veins and tendons start to show through and the hand looks older than you feel. Hyaluronic acid fillers such as Juvederm, Restylane and Teosyal replace that lost volume and soften the sharp ridges. Radiesse, a calcium-hydroxylapatite biostimulator, plumps the hand straight away and then stimulates your own collagen for a gradual, longer-lasting result.

Downtime is minimal, and the improvement keeps developing over the following weeks as the collagen builds. It is the same volumising principle we use on the face, so if you are exploring hand work you may also be considering dermal fillers for other areas.

Related treatments at Dr Joney De Souza: Profhilo and dermal fillers.

Learn more about dermal fillers

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Profhilo & Skin Boosters for Hands

Thin, dull or crepey skin on the hands is a quality problem rather than a volume one, so it needs a different answer. Injectable skin boosters such as Profhilo and Teosyal Redensity deliver deep hydration and remodel the skin over a short course, improving thickness, elasticity and glow without adding structural bulk.

Most patients have a course of two sessions spaced around four weeks apart. The result is skin that looks fresher and feels more supple, and it pairs naturally with volume work when both are needed.

Learn more about Profhilo

PicoSure Laser & IPL for Hands

Brown age spots on the backs of the hands are the clearest giveaway of years spent in the sun, and they respond well to light-based treatment. PicoSure laser and Palomar IPL target the pigment so your body can clear it, evening out skin tone and refreshing the overall look. The focus here is colour and texture rather than volume.

A short course gives the best results, protected afterwards by daily sun care so the pigment does not simply return. Many patients treat their hands alongside MaxG IPL photorejuvenation on the face for a matching, even tone.

Learn more about PicoSure

Enerpeel Chemical Peels & HydraFacial for Hands

Not every hand needs injections or laser. Chemical peels and a dedicated HydraFacial for the hands improve surface pigmentation, brightness and rough texture with little to no downtime, which makes them a gentle first step or a comfortable way to maintain results between other treatments.

Your practitioner will advise how often to repeat them so the improvement holds. These surface treatments sit happily alongside injectable or laser work as part of a longer-term plan.

Learn more about peels & facials

Hand Rejuvenation Before & After Results in Marylebone

Individual results vary from person to person. Every treatment plan is tailored to the patient after a consultation with our clinical team.

Before
After

Skin Booster results

Before
After

Frequently Asked Questions

What is the best treatment for hand rejuvenation?

There is no single best treatment, because it depends on your main concern. Volume loss is treated with fillers or Radiesse, skin quality with Profhilo or skin boosters, and pigmentation with PicoSure or IPL. Many patients at Dr Joney De Souza combine treatments for the most natural result, and your consultation will map out which order makes sense for you. Hand rejuvenation will not remove veins the way a vascular procedure does; it softens their appearance by restoring volume around them.

Does hand rejuvenation treat prominent veins on the hands?

Yes. Restoring volume to the back of the hand with

dermal fillers or Radiesse softens the look of prominent veins and tendons. This is different from vein removal, and it does not close or destroy the veins themselves. The aim is to smooth and re-contour the hand so the veins sit less obviously beneath a fuller, more even surface.

How do I get rid of age spots on my hands?

Age spots and sun damage are treated with PicoSure laser or IPL, which break down excess pigment so the skin clears it over the following weeks. A short course usually gives the best results, and daily sun protection helps keep the spots from returning. If pigmentation is your main worry, it is worth reading more about how we approach

age spots across the hands and face.

Is hand rejuvenation painful, and is there downtime?

Most treatments are well tolerated, with only brief discomfort during injections or laser, and cooling or numbing can be used to keep you comfortable. Downtime is minimal, so mild swelling, redness or bruising typically settles within a few days. Heavier bruising is uncommon but possible after volume work, so it is sensible to leave a little room before a big event.

How long do hand rejuvenation results last?

It varies by treatment. Hyaluronic acid fillers last around 9 to 18 months, Radiesse builds collagen for longer-term improvement, skin boosters last several months, and laser pigmentation results are long-lasting with good skincare. Hands are used and washed constantly, so ongoing sun protection and occasional maintenance help the results hold for as long as possible.

Who performs hand rejuvenation at the clinic, and is it safe?

It is safe when carried out by qualified medical professionals after a proper assessment. Carried out by Dr Joney De Souza or a member of our clinical team. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Every treatment follows a detailed consultation to assess your skin health, circulation and suitability before anything is recommended.

 4.9 ★★★★★

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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I’ve known Dr. Joney de Souza for years and can’t recommend him highly enough. He’s a true expert in aesthetics, always professional, innovative, and genuinely caring. His treatments are subtle, natural, and always tailored to your needs. A standout in London’s aesthetic scene!
Osmar Pinheiro Bacelar Junior
Osmar Pinheiro Bacelar Junior
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I had treatment at Dr. Joney De Souza’s clinic one month ago and had a fantastic experience. Dr. De Souza was friendly, highly knowledgeable, and made me feel completely comfortable and at ease throughout the process. His great sense of humor also helped create a relaxed atmosphere. I’m really happy with the results and will definitely be coming back for regular visits. Highly recommend this clinic!
Daluna London
Daluna London
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The clinic is so very welcoming and really listens to how and what you would like to achieve, i have had several facial treatments and it has made such a difference to my confidence. David and everyone in the clinic are professional and experts in what they do, they treat you with a really personal service. My skin has never looked so clear or glowing .. I’ve had people stop and ask me what and where do I have my treatments .. thank you
Jayne Gates
Jayne Gates
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I had an excellent experience with Dr. Joney de Souza and his team. From start to finish, they were incredibly supportive, making me feel at ease throughout the entire process. Dr. Joney has both a sharp eye and a soft hand, striking the perfect balance between precision and gentleness. The team’s expertise speaks for itself, and their approach is as refined as it is reassuring. Highly recommended.

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Why PicoSure is Roma’s ultimate favorite treatment to perform...🌟

“I love working with the PicoSure Laser because it delivers incredible results with minimal downtime. From pigmentation and acne scars to skin rejuvenation and tattoo removal, it’s a versatile technology that helps clients achieve brighter, healthier-looking skin. Seeing their confidence grow after their treatment is the most rewarding part of my work.”

— Roma, Skin Therapist

Treat your skin to Roma’s top recommendation ! ✨Lip flip vs lip filler. Which one is right for you? Swipe through to find out 👉

Two very different treatments. Two very different results. And yet they are confused for each other constantly, so let us clear it up...

The lip flip
A lip flip uses a small amount of muscle-relaxing product placed into the muscle just above the upper lip. Rather than adding volume, it causes the upper lip to gently roll outward, creating the appearance of a fuller, more defined lip without any filler being used. The result is a subtle soft enhancement that works particularly well for anyone who feels their upper lip disappears when they smile, or who wants a more natural look without added volume. 

Lip filler
Lip filler uses hyaluronic acid to add volume, shape and definition to the lips. It can be used to enhance the overall size of the lips, define the lip border, correct asymmetry or restore volume that has been lost over time. The results are immediate and can be tailored precisely to what you are looking for - whether that is a subtle, natural enhancement or something more noticeable. 

So which one is for you? The best way to find out is by booking a consultation with us where your individual anatomy, goals and expectations can be properly assessed.

📍Marylebone, London | 020 7043 0748 📱The SPF market can feel overwhelming, and we completely understand why 👇

Too many options, too many textures, too many excuses. So let us make it simple.

We hear the same things all the time. It breaks me out. It leaves a white cast. It feels greasy. I just cannot be bothered. And honestly? Every single one of those concerns is valid. But in 2026, none of them are reasons not to wear SPF anymore.

The ZO Skin Health SPF range, which we stock here at Dr Joney De Souza Skin & Laser, has an option for every single skin type, concern and lifestyle. And we mean that.

💭Oily or acne-prone skin? The Sheer Fluid SPF 50 is lightweight, oil-free and non-comedogenic. No breakouts. No shine.

💭Want your SPF to double as a primer? The Sunscreen + Primer SPF 30 creates a flawless base for makeup in one step.

💭Need something for active days or the beach? The Daily Sheer SPF 50 is water resistant and suitable for all skin tones with zero white cast.

💭Want a little coverage too? The Smart Tone SPF 50 adapts to your skin tone for a subtle, skin-perfecting finish.

And for anyone who just cannot be bothered with reapplying? The Sunscreen + Powder SPF 30 is a brush-on powder that goes straight over your makeup, tops up your protection and controls shine at the same time. No fuss. No excuses.

There is an SPF for everyone. Come and find yours today 🤍Profhilo vs Profhilo Structura - what is the difference? 👉

Both are injectable treatments containing hyaluronic acid. Both are produced by the same manufacturer. And both deliver beautiful, natural results. But they are not the same treatment, and understanding the difference is important when it comes to choosing the right one for your skin.

🫧 Profhilo
Profhilo is a skin booster. Its primary purpose is to deeply hydrate the skin, improve overall skin quality and stimulate the production of collagen and elastin. It spreads through the tissue to treat a wide area, leaving the skin looking more radiant, plump and youthful. It is suitable for a broad range of patients and is particularly effective for anyone experiencing dullness, dehydration or a general loss of skin glow.

🫧 Profhilo Structura
Profhilo Structura is specifically designed to address skin laxity and loss of firmness. It contains a higher concentration of high molecular weight hyaluronic acid, which works to remodel the deeper structural layers of the skin, restoring lift, firmness and definition in areas where the skin has begun to lose its architecture over time. It is particularly effective for the cheeks, jawline and neck.

Which one is right for you?
If your primary concern is skin quality, hydration and radiance, Profhilo is likely the right starting point. If you are noticing a loss of firmness, definition or lift, Profhilo Structura may be the more appropriate choice. For many patients, the two work beautifully together as part of a combined treatment plan.

The best way to find out is a thorough consultation with one of our medics 🤍

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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